|Open your enemies|
Sharp Key is an active item.
- Sharp Key is not affected by picking up a Golden Key. It will still cost one key to throw and cannot be used once the key counter reaches 0.
- Cricket's Body: Sharp Key splits into 4 smaller ones, which each has an identical effect but with less damage.
- Homing Tears: Sharp Key homes on enemies.
- Ipecac: Sharp Key explodes on impact with obstacles, enemies, or walls.
- Rubber Cement: Sharp Key can bounce off walls and enemies, overriding its piercing effect.
- Spectral Tears: Sharp Key can pass through obstacles, but will no longer destroy them.
- Tiny Planet: Sharp Key orbits around Isaac.