Screamers are tall, greyish enemies that slowly move around the room. If Isaac gets too close to one, it will scream, paralyzing Isaac.
After he screams, its speed will drastically increase, and he will try to chase Isaac down. It will also gain a black aura around it, that will slow Isaac down if he's within it.
- It is recommended to kill this enemy at a distance to avoid angering it.
- It is possible to trigger his scream without being paralyzed, provided one has enough speed.
- Screamers appear to be based on the ReDead enemies from The Legend of Zelda, who are also tall, skinny enemies that initially seem harmless until they release a scream and slowly walk to the now paralyzed player to attack him.