Pickups

Antibirth adds a few new types of pickups.

Hearts

Immortal Heart

Immortal Hearts are white hearts which append to the end of the health bar like soul hearts.

Immortal Hearts always take two hits to be fully depleted, and will regenerate from half to full upon clearing a room.

Rotten Heart

Rotten Hearts are infested red hearts which fill up a full heart container. If a Rotten Heart is picked up at full health, it will replace the rightmost red heart.

For each Rotten Heart possessed upon clearing a room, two blue flies will spawn. You cannot have half a Rotten Heart; they are always depleted in one hit.

Depleting a Rotten Heart will not count against Devil Deal Chance when it's the rightmost red heart, since it is technically not a red heart.

Rotten Hearts are unlocked by entering the Corpse for the first time.

Pills

Three new pill effects were introduced in Antibirth.

Pill	Effect
Experimental Pill	Increases one random attribute and decreases a different random attribute. Will not decrease attributes with PHD.
Shot Speed Down	Decreases shot speed.
Shot Speed Up	Increases shot speed.

Notes

• It is possible for an Experimental Pill to decrease health while Isaac has one heart container, killing him.

Runes

Multiple new runes were added to Antibirth.

Rune	ID	Icon	Message	Unlocked by completing	Effect
Rune of Gebo	60		"Charity"	4x. Bloody Mary	Donates money to a machine
Rune of Kenaz	61		"Pestilence"	2x. Scat Man	Poisons all enemies in the room
Rune of Fehu	62		"Wealth"	3x. Turbo	Turns all the pickups in the room into coins
Rune of Othala	63		"Legacy"	9x. Seeing Double	Rewards a random item that Isaac already holds
Rune of Ingwaz	64		"Treasure"
Rune of Sowilo	65		"Renewal"