Items

Items are an integral part of game-play in The Binding of Isaac: Rebirth. They modify Isaac's Attributes, grant or modify Tear Effects, and much more. Antibirth adds over 90 new items.

Activated Collectibles

Name	Icon	Description	Recharge
Sulfur		Grants Brimstone for the current room.	3
Fortune Cookie		Displays a random fortune, and has a chance to drop a soul heart, card, rune or trinket.	2
Book Of Despair		Halves tear delay for the current room.	3
D12		Re-rolls obstacles into other obstacles.	3
Bowl of Tears		Fires a cluster of tears. Each tear shot by Isaac increases item charge by one.	6
Damocles		Spawns a sword above Isaac's head, which doubles all item pedestals while it remains. After Isaac takes damage, the sword can randomly fall at any point, instantly killing him.	One time use
Free Lemonade		Creates a large puddle of lemonade that damages enemies.	4
Red Key		Creates a red colored room on the map near Isaac's current position. The room can be anything from a regular encounter room to a Devil Room.	3
Black Mushroom		Reduces tear delay but distorts the screen for a length of time. Can be used multiple times to stack the effect. Tear delay is reset on changing rooms; however, the distortion persists.	1 second
Book Of Virtues		Summons a temporary flame familiar that fires spectral tears, deal contact damage to enemies and blocks enemy shots. Flames are consumed after taking a certain amount of damage or touching enemies. A maximum of 16 flames can be active at once: one inner ring of eight and an outer ring of eight.	2
Alabaster Box		Gains charges through soul, black, and white hearts. After 6 full hearts are absorbed, it will spawn varying amounts of consumables and items from the Angel room pool.	One time use, 12 charges to use
Mom's Bracelet		Allows Isaac to grab obstacles and throw them, damaging enemies.	1 second
The Scooper		Summons a Peep familiar for the current room, which leaves a trail of red creep.	3
Eternal D6		Rerolls all items in the room. Each item has a chance to disappear instead.	3
Voodoo Pin		Hurts Isaac without actually damaging him, activating any items that would trigger upon taking damage.	2
Sharp Key		Allows Isaac to consume keys and fire them at enemies. Adds 5 keys.	0
Mega Mush		Gigantifies Isaac, increasing damage and range while lowering tears, granting invulnerability, and allowing Isaac to crush enemies and obstacles he walks on. The effect persists between rooms.	12
Meat Cleaver		Splits all enemies in a room into 2 smaller versions of themselves with lower health.	2
Stitches		Spawns a familiar that flies diagonally across the room, switching direction upon hitting walls. Activating the item swaps the positions of Isaac and Stitches.	3 seconds
R Key		Upon use, restarts the game to the first floor, keeping all previously collected items. Game timer does not restart. Allows angels rooms to be found even if the previous run included devil deals.	One time use
Eraser		Throws an eraser which instantly kills the first enemy it hits, also killing all other copies in the room. If it hits a non-boss, prevents them from spawning for the rest of the run.	One time use
Yuck Heart		Upon use, grants a rotten heart.	4
Magic Skin		Generates one item from the current room's item pool and gives Isaac a broken heart, which permanently decreases the maximum health limit.	6

Passive Collectibles

Name	Icon	Description
2Spooky		Enemies near Isaac will be inflicted with Fear, causing them to flee from him.
Schoolbag		Grants an extra active item slot.
Eye Sore		Frequently fire tears in random directions in addition to regular tears. Can fire up to three extra tears.
120 Volt		Whenever an enemy is shot, it will zap other enemies near them, dealing damage.
It Hurts		Taking damage causes Isaac to release a ring of bloody tears and increases fire rate for current room.
Almond Milk		Upgrades fire rate immensely but significantly decreases damage, and tears are given random worm effects.
Rock Bottom		Lowers all stats to their base value. Prevents stats from being lowered the rest of the run.
Enigma Bombs		Grants 5 bombs. Bombs explode with a random bomb effect.
A Bar Of Soap		Increases tears and shot speed.
Paschal Candle		Increases tears for each room completed without taking damage. Resets on taking damage.
Blood Oath		Stabs Isaac at the beginning of each floor, draining all but half a heart of his red hearts. Increases damage and speed for the floor based on the amount drained.
Playdoh Cookie		Grants multicolored tears, which can be normal, petrifying, homing, poisoning, or fear-inducing based on their color.
Orphan Socks		Grants +0.15 Speed and two Soul Hearts. Isaac can walk on harmful floor effects without taking damage.
Eye Of The Occult		Increases damage. Tears can be controlled mid-flight using the fire keys.
Immaculate Heart		Adds a heart container and increases damage. Isaac fires spectral orbiting tears alongside normal tears.
Monstrance		Isaac emits an aura that damages nearby enemies.
The Intruder		A familiar burrows in Isaac's head, firing 4 slowing tears. Upon taking damage, there's a chance it will burst out of Isaac's head, spawning blue spiders and chasing enemies for the current room.
Dirty Mind		Destroying poop spawns friendly Dips that follow Isaac and damage enemies. Destroying different types of poop spawns different Dips with special effects.
Spirit Sword		Instead of tears, Isaac swings a sword. Charging does a spin attack and fires a projectile, and a projectile is fired with every swing if Isaac has no empty red hearts.
Psy Fly		Catches enemy shots and flings them back at enemies as homing tears.
Rocket In A Jar		Grants 5 bombs. Bombs become rockets that fly in the direction Isaac is currently looking.
Jacob's Ladder		Generates a ladder in the starting room of all future floors, which leads to a special Angel Room.
Menorah		Spawns a familiar that grants an extra tear per shot for each lit candle. A candle is lit each time Isaac takes damage, up to 7. Being hit again will reset the menorah and release blue flames.
Sol		Reveals the location of the Boss room. Upon defeating a boss, activates XIX - The Sun, fully recharges Isaac's active item, and grants bonus damage and luck for the rest of the floor.
Luna		Adds one extra Secret Room and one Super Secret Room on each floor.
Mercurius		Doors stay open after entering a room, even with enemies in it, allowing Isaac to leave any time. Increases speed.
Venus		Adds one Red heart. Enemies near Isaac are Charmed, causing them to attack other enemies.
Terra		Isaac's tears become rocks that have increased knockback and deal variable damage, and have a high chance to destroy obstacles.
Mars		Charge in a direction by double-tapping the movement key, becoming invulnerable and damaging enemies. There's a short cooldown before Isaac can dash again.
Saturnus		Isaac is surrounded by an aura which has a chance to absorb incoming enemy tears. It begins with 7 orbiting tears when entering a new room.
Uranus		Isaac shoots ice tears, which freeze enemies they kill. Frozen enemies slide away and explode into ice shards when touched.
Pluto		Significantly shrinks Isaac, allowing him to squeeze between objects and making some enemy shots pass over him. Increases tears and speed, but decreases range.
Voodoo Head		Additional curse rooms can spawn each floor.
Eye Drops		Lowers the tear delay in Isaac's left eye, causing his eyes to fire at different rates.
Act Of Contrition		Grants an Immortal Heart and increases tears. Angel Rooms can appear even if a Devil deal has been taken.
Member Card		Opens a trapdoor with a ladder in every shop. The trapdoor leads to a special shop room, which sells multiple items or pickups for random prices. Sold collectibles don't have to be from the Shop pool.
Battery Pack		Recharges Isaac's currently held active item and drops 2-4 batteries.
Oculus Rift		Adds a chance to fire tears that summon rifts wherever they land. Rifts attract enemies, enemy shots, Isaac's tears, and pickups. They also deal contact damage to enemies caught in them.
Boiled Baby		Grants a familiar similar to a Boil that periodically fires bursts of bullets.
Freezer Baby		Grants a familiar that fires shots that freeze enemies. Frozen enemies explode into ice shards when touched.
Bird Cage		The first time Isaac takes damage in a room, the familiar leaps on an enemy, dealing damage and releasing a rock wave. For the rest of the room, it chases enemies similar to Dead Bird.
Donkey Jawbone		Isaac does a spin attack that damages nearby enemies whenever he takes damage. Killed enemies have a chance to drop a red heart.
Lost Soul		Spawns a Lost familiar that follows Isaac. It dies if hit by an enemy, regenerating on the next floor. If it survives an entire floor, it grants a random reward.
Blood Bombs		Grants 1 heart container. Bombs create puddles of damaging red creep upon exploding. If Isaac has no bombs, bombs can be placed at the cost of half a heart.
Lil' Dumpy		Grants a familiar that loosely follows Isaac. It farts when hit by enemy attacks, poisoning or stunning enemies and sending it bouncing away.
Bird's Eye		Adds a chance to shoot a fire instead of a tear, which pierces and can block enemy shots, diminishing in size as it does.
Lodestone		Adds a chance to fire magnetizing tears. Magnetized enemies attract other enemies, Isaac's tears, and enemy shots including their own.
Rotten Tomato		Tears have a chance to mark enemies. Marked enemies will be attacked by other enemies.
Birthright		Has a different effect for each character.
Red Stew		Restores all red heart containers. Grants an enormous damage boost that wears off over time.
Sausage		All stats up.
Booster Pack		Spawns 3 tarot cards.
Knife Piece 1		Has no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Knife Piece 2		Has no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Knife Piece 3		Has no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Bot Fly		Grants a familiar that fires shielded tears at incoming bullets.
Evil Charm		Grants +3 luck.
Stone Bombs		Grants 5 bombs. Bombs release rock waves in the cardinal directions, which can damage enemies, destroy obstacles, and damage Isaac.
Knockout Drops		Adds a chance to fire fist tears, which have massive knockback and briefly stun enemies.
Akeldama		While in an uncleared room, Isaac forms trails of bloody tears that drag behind him, bursting and dealing damage upon contact with enemies.
Revelation		Adds 2 Immortal Hearts, grants flight, gives tears a Brain Worm-like homing effect, decreases range and increases shot speed.
Consolation Prize		Increases Isaac's lowest stat and grants either 3 coins, 1 bomb, or 1 key depending on what Isaac has the least of.
Tinytoma		A large familiar slowly orbits Isaac. Upon taking enough damage, it splits into two smaller orbitals. If they take enough damage, they burst into blue spiders and the large orbital respawns.