The Binding of Isaac: Antibirth Wiki
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Items are an integral part of game-play in The Binding of Isaac: Rebirth. They modify Isaac's Attributes, grant or modify Tear Effects, and much more. Antibirth adds over 90 new items.

Name Icon Description Recharge
MucormycosisMucormycosis IconUpon enemies' death, they release a cloud of gas that damages and poisons other enemies.
2Spooky2Spooky IconEnemies near Isaac will be inflicted with Fear, causing them to flee from him.
SchoolbagSchoolbag IconGrants an extra active item slot.
SulfurSulfur IconGrants Brimstone for the current room.3
Fortune CookieFortune Cookie IconDisplays a random fortune, and has a chance to drop a soul heart, card, rune or trinket.2
Eye SoreEye Sore IconFrequently fire tears in random directions in addition to regular tears. Can fire up to three extra tears.
120 Volt120 Volt IconWhenever an enemy is shot, it will zap other enemies near them, dealing damage.
It HurtsIt Hurts IconTaking damage causes Isaac to release a ring of bloody tears and increases fire rate for current room.
Almond MilkAlmond Milk IconUpgrades fire rate immensely but significantly decreases damage, and tears are given random worm effects.
Rock BottomRock Bottom IconAll stats down. Prevents stats from being lowered the rest of the run.
Enigma BombsEnigma Bombs IconGrants 5 bombs. Bombs explode with a random bomb effect.
A Bar Of SoapA Bar Of Soap IconIncreases tears and shot speed.
Book Of DespairBook Of Despair IconIncreases tears for the current room.3
D12D12 IconRe-rolls obstacles into other obstacles.
Paschal CandlePaschal Candle IconIncreases stats for each room completed without taking damage. Resets on taking damage.
Bowl of TearsBowl of Tears IconFires a cluster of tears. Each tear shot by Isaac increases item charge by one.6
Blood OathBlood Oath IconStabs Isaac at the beginning of each floor, draining all but half a heart of his heart containers. Increases damage and speed.
Playdoh CookiePlaydoh Cookie IconAdds random effects to tears.
Orphan SocksOrphan Socks IconIsaac gains 2 spirit hearts and can walk on harmful floor effects.
Eye Of The OccultEye Of The Occult IconIncreases damage. Tears can be controlled mid-flight using the fire keys.
Immaculate HeartImmaculate Heart IconFire orbiting tears along with normal tears.
MonstranceMonstrance IconIsaac emits an aura that damages nearby enemies.
The IntruderThe Intruder IconIsaac will now fire four slowing tears in addition to normal tears. Upon taking damage multiple times in one room, Isaac's head will pop, spawning friendly spiders and a familiar that leaps at enemies.
Dirty MindDirty Mind IconDestroying poop spawns friendly Dips that follow the player and damage enemies. Destroying different types of poop spawns different Dips with special effects.
DamoclesDamocles IconSpawns a sword above Isaac's head. After a period of time, it will instantly kill him. While he is alive, he receives bonus items from bosses and treasure roomsOne time use
Free LemonadeFree Lemonade IconCreates a large puddle of lemonade that damages enemies.4
Spirit SwordSpirit Sword IconReplaces Isaac's tears with a sword he can swing in front of him. Holding an attack button charges a spin attack. If Isaac is at full health, it also shoots a projectile when swung. Only one projectile can be active at once.
Red KeyRed Key IconCreates a red colored room on the map near Isaac's current position. The room can be anything from a regular encounter room to a Devil Room.3
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Black MushroomBlack Mushroom IconReduces tear delay but distorts the screen for a length of time. Can be used multiple times to stack the effect. Tear delay is reset on changing rooms; however, the distortion persists.? seconds
Rocket In A JarRocket In A Jar IconGrants 5 bombs. Bombs become rockets that fly in the direction Isaac is currently looking.
Book Of VirtuesBook Of Virtues IconSummons a temporary flame familiar that fires spectral tears, deal contact damage to enemies and blocks enemy shots. Flames are consumed after taking a certain amount of damage or touching enemies. A maximum of 16 flames can be active at once: one inner ring of eight and an outer ring of eight.2
Alabaster BoxAlabaster Box IconGains charges through soul, black, and white hearts. After 6 full hearts are absorbed, it will spawn varying amounts of consumables and items from the Angel room pool.One time use, 12 charges to use
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MenorahMenorah IconSpawns a menorah familiar with one candle lit. Each time Isaac is hit, another candle is lit, and he fires an additional tear, up to 7-shot tears. Being hit an additional time will reset the menorah.
SolSol IconActivates the Sun tarot card upon defeating a boss.
LunaLuna IconAdds one extra Secret Room and one Super Secret Room on each floor.
MercuriusMercurius IconDoors stay open after entering a room, even with enemies in it, allowing Isaac to leave any time. Increases speed.
VenusVenus Icon
TerraTerra IconIsaac's tears become rocks. The tears can also destroy rocks.
MarsMars IconGain the ability to charge by double-tapping in a direction. Isaac is invincible during the charge and deals significant damage. Can be used multiple times per room with a short recharge time.
SaturnusSaturnus IconIsaac is surrounded by an aura which grants 7 orbiting tears when entering a new room and has a chance to absorb incoming enemy tears.
UranusUranus IconIsaac shoots ice tears.
PlutoPluto IconDecreases Isaac's size to the point where many tears will fly over Isaac. Increases tears and speed, and decreases range.
Voodoo HeadVoodoo Head IconAdditional curse rooms can spawn each floor.
Eye DropsEye Drops IconIncreases tears. Tears fire at different rates from each of Isaac's eyes.
Act Of ContritionAct Of Contrition IconGrants an Immortal Heart and increases tears.
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Battery PackBattery Pack IconRecharges Isaac's currently held active item and drops 2-4 batteries.
Mom's BraceletMom's Bracelet IconAllows the player to grab obstacles and throw them, damaging enemies.0
The ScooperThe Scooper IconOn use, summons a familiar the same as The Peeper that floats around the room.3
Oculus RiftOculus Rift IconAdds a chance to fire tears that summon rifts wherever they land. Rifts attract enemies, enemy shots, Isaac's tears, and pickups. They also deal contact damage to enemies caught in them.
Boiled BabyBoiled Baby IconGrants a familiar similar to a Boil that periodically fires bursts of bullets.
Freezer BabyFreezer Baby IconGrants a familiar that fires shots that freeze enemies. Frozen enemies explode into ice shards when touched.
Eternal D6Eternal D6 IconRerolls items with chance of disappearing.3
Bird CageBird Cage IconUpon taking damage the first time in a room, the familiar leaps from Isaac's head, targets an enemy, and lands on them, dealing damage and releasing a rock wave. For the rest of the room, the familiar targets and attacks enemies similar to Dead Bird.
Donkey JawboneDonkey Jawbone IconWhenever Isaac takes damage, a spin attack will damage enemies around him.
Lost SoulLost Soul IconSpawns a familiar version of The Lost that follows Isaac. Upon being hit, it instantly dies, regenerating on the next floor. If it survives an entire floor, it grants a random reward.
Blood BombsBlood Bombs IconGrants 5 bombs. Bombs create puddles of damaging red creep upon exploding. If Isaac has no bombs, bomb can be placed at the cost of half a heart.
Lil' DumpyLil' Dumpy IconGrants a familiar that loosely follows the player. Farts when hit by enemy attacks.
Bird's EyeBird's Eye IconAdds a chance to spit a large fire whenever Isaac fires a tear.
LodestoneLodestone IconAdds a chance to fire magnetizing tears. Magnetized enemies attract other enemies, Isaac's tears, and enemy shots including their own.
Rotten TomatoRotten Tomato IconTears have a chance to mark enemies. Marked enemies will be attacked by other enemies.
BirthrightBirthright IconGrants different effects depending on which character you're playing as.
Voodoo PinVoodoo Pin IconHurts Isaac without actually damaging him, activating any items that would trigger upon taking damage.2
Red StewRed Stew IconRestores all red heart containers. Grants an enormous damage boost that wears off over time.
SausageSausage IconAll stats up.
Sharp KeySharp Key IconAllows Isaac to consume keys and fire them at enemies. Adds 5 keys.0
Booster PackBooster Pack IconSpawns 3 tarot cards.
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Knife Piece 1Knife Piece 1 IconHas no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Knife Piece 2Knife Piece 2 IconHas no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Knife Piece 3Knife Piece 3 IconHas no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Bot FlyBot Fly IconGrants a familiar that fires shielded tears at incoming bullets.
Meat CleaverMeat Cleaver IconSplits all enemies in a room into 2 smaller versions of themselves with lower health.2
Evil CharmEvil Charm IconGrants +3 luck.
Stone BombsStone Bombs IconGrants 5 bombs. Bombs release rock waves in the cardinal directions, which can damage enemies, destroy obstacles, and damage Isaac.
StitchesStitches IconSpawns a familiar that flies diagonally across the room, switching direction upon hitting walls. Activating the item swaps the positions of Isaac and Stitches.3 seconds
R KeyR Key IconSingle use. Upon use, restarts the game to the first floor, keeping all previously collected items. Game timer does not restart. Allows angels rooms to be found even if the previous run included devil deals.One time use
Knockout DropsKnockout Drops IconAdds a chance to fire fist tears, which have massive knockback and briefly stun enemies.
EraserEraser IconPrevents an enemy from appearing for the rest of the run.
Yuck HeartYuck Heart IconUpon use, grants a rotten heart.4
AkeldamaAkeldama IconWhenever Isaac fires a shot, a bloody tear will spawn behind him. Multiple tears will form a trail of tears that drags behind Isaac as he moves, bursting and dealing damage upon contact with enemies. Multiple trails can be formed.
Magic SkinMagic Skin IconGenerates one item from the current room's item pool and gives Isaac a broken heart, which permanently decreases the maximum health limit.6
RevelationRevelation IconAdds 2 Immortal Hearts, grants flight, decreases range and increases shot speed.
Consolation PrizeConsolation Prize IconRaises Isaac's current lowest stat. Can also drop a consumable for whichever Isaac has the least of.
TinytomaTinytoma IconA large orbital that slowly orbits Isaac. Upon taking enough tear or contact damage, the orbital splits into two smaller ones that orbit opposite of each other. If the small orbitals take enough damage, they burst into a few blue spiders, and the large orbital respawns.


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