- Spits a large cluster of blood shots at the player along with a special meat projectile that spawns a Globin in its goo stage.
- Spits a big bloodshot towards Isaac which stops in place after traveling a short distance before splitting into 8 smaller shots in all directions.
Upon death, the Cohort splits into 4 more Globins in their goo stage.
- The cluster shot attack along is telegraphed by the Cohort scrunching his face and gazing at the player with a single eye, resembling that of a Gazing Globin. However, for the rest of the time, the Cohort will have both eye sockets empty.
- Unlike Monstro, the Cohort can not leap high in the air to land directly on top of Isaac.
- Cohorts have higher HP than Oobs, which have the highest HP of any monster in the base game.
- Cohorts have 125 HP, while Oobs only have 100 HP.