Bosses

This article is about the changes of "The Binding of Isaac: Antibirth". For the main page, see Bosses.

Bosses are strong monsters found in boss rooms at the end of a floor. The boss at the end of the floor must be defeated to advance to the next floor. The boss for a particular floor is chosen from the pool of bosses for the environment of the floor. Upon defeat, most bosses will drop an item from the boss item pool.

Antibirth adds 16 new bosses and a few variants on existing bosses.

Normal Chapters

Chapter 1

Baby Plum

Chapter 3

The Pile	Reap Creep

Downpour

Wormwood	Beelzeblub	The Rainmaker	The Haunt

Mines

Tuff Twins	Great Gideon	Hornfel	Reap Creep

Mausoleum

Floor 1

The Heretic	The Visage	The Siren	The Pile

Floor 2

Mausoleum Mom

Corpse

Floor 1

The Scourge	Rotgut	Chimera

Floor 2

The Witness

Universal

These bosses have a chance of replacing a boss from an environment pool, including Antibirth floors.

The Fallen